Diabetic Ulcer

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Clinical Presentation

Diabetic ulcers can be quite problematic. It is not uncommon for people with diabetes who have developed forefoot ulcers, to ultimately end up with a partial or complete amputation of their foot and even the leg, as a result of the ulcer and spread of infection from the ulcer.

Patients with longstanding diabetes, who have lost sensation or have altered sensation in their foot, are at risk for developing a diabetic plantar ulceration. Quite often, patients with diabetes do not appreciate that they have altered or diminished sensation in their foot. The altered sensation prevents them from sensing pain, such as they would normally experience with a blister on their foot or with shoes that do not fit appropriately. Therefore they end up with blistering and subsequent breakdown of skin and deeper tissues over a localized pressure area of the foot, and this can become an ulcer. Often, the area starts off as a callus, or if it occurs quickly, it may appear as a simple blister. However, when the blistered skin is removed, it will reveal a deep ulceration. Patients who lost the protective sensation are therefore at a greater risk of developing an ulcer especially if their feet also have deformities such as a bunion or hammer toes.

Physical Examination

Physical examination focuses on the location of the ulcer as well as the depth. It is important to assess whether or not the ulcer extends down to the bone, which could lead to osteomyelitis (bone infection). A foul odor or redness spreading from the ulcer up the foot or the leg signifies serious infection. Typically, the ulcers will occur over a prominent area, often associated with the base of one or more toes, although ulcers in other areas can occur. They can occur over the top of a deformed toe or at its tip. At times these occur under ball of the foot again related to an area that is prominent and gets disproportionately overloaded such as in a foot with high arch. Essentially, any area of the foot that is subject to concentrated repetitive force is at risk for developing a diabetic ulceration. Risk factors for developing an ulcer include not only include prominent areas taking disproportionate amount of force but also stiff or tight muscles and joints such as a tight calf muscle (equinus contracture) which serves to increase the lever force of the foot, driving the forefoot into the ground with more force. An assessment of the patient’s sensation and circulation is also important. It is also important on physical exam to assess the patient’s opposite foot, as it may have problems that have not yet been diagnosed. At times unbeknown to the patients there can be foreign objects such as a pill or a small rock or a nail embedded in the insole that can contribute to the ulcer. A thickened and overgrown toe nail often due to fungal infections can also lead to increased pressure due to crowding in the toe box and an ulcer.

Imaging Studies

Radiographs will usually be taken to assess whether there is any obvious bony or joint involvement. Sometimes, an MRI is indicated to look for extension of the soft tissue infection or a deep abscess if this cannot be determined by examination. Occasionally, a bone scan is indicated, although very often the results of the bone scan will not change the management, and may not reveal any information that cannot be obtained from a detailed physical examination.


Treatment is designed to allow the ulceration to resolve. Essentially, this involves removing the pressure that caused the ulcer in the first place and thus off-loading the area of ulceration. This is typically done with a total contact cast or a foot wear modification that removes the offending pressure. It may be possible to fit the patient with a removable diabetic walker boot. In each instance, the goals are to offload the affected area and allow the tissues to heal. If this is done, it will often allow the ulceration to heal within 6-8 weeks for a full-blown ulceration.

The patients that are at risk for ulcerations, but have not yet developed an ulcer, may be treated with inserts that are designed to disperse the force away from the affected area. The lining of these inserts are typically made of a soft material called plastizote. It takes on the shape of the foot and helps to spread the force away from the ulcerated area.

Patient education is a very important component of managing diabetic ulcerations and patients with neuropathy. Ideally, ulcerations should be treated with prevention. Patients with diabetes, and particularly those who had altered sensation in their feet should:

  • Always wear appropriate footwear. Shoes should not be too tight. They should not have any pressure points and they should have a good insert that helps disperse the force of walking throughout the sole of the foot. The upper should have a stretchy material such as a soft leather or fabric.
  • Check the soles of their feet daily to look for any potential areas of skin breakdown or new blister formation. Check the insoles of the footwear regularly. Wear white seamless socks, which avoid pressures due to the seam and show up any discharge such as blood from a blister easily on the white color.
  • Always wear shoes. Shoes will allow them to avoid walking on hot surfaces. Walking bare feet on a hot surface that is not recognized because of their altered sensation is another way patients will have breakdown in the skin over the sole of their feet.
  • Keep their toenails well trimmed. This typically involves keeping the toes trimmed, either straight across or with a gentle contour in the shape of the toe, and ensuring that the inside and outside edges of the toenails do not catch and jab into the associated skin.
  • Have regular foot checkups

Treatment of the ulceration may also involve trimming (debridement) of the callus or necrotic tissue. Usually, this can be done in the clinic, although sometimes it may need to be done in the operating room if the infection involves the bone, and there is some need to remove part of the infected bone. In addition, it is increasingly common to perform a calf lengthening or Achilles tendon lengthening to help decrease the pressure that the forefoot is experiencing. This can be highly successful, although it does need to be done with caution to prevent over lengthening. This is done as a formal operative procedure.

Patients with diabetes and altered sensation of their feet who notice a breakdown in the skin should see a physician immediately. This is an urgent situation. The physician may want to prescribe antibiotics or they may consider simply off loading this area for a short period of time, allowing the area of skin breakdown to heal. Small areas of breakdown in the skin can become major limb threatening problems in a matter of days, if they are not carefully attended to.

Figure 1: This patient is likely to get an ulcer at the tips of the right second and third toes
diabetic ulcer
Figure 2: This patient is overloading the forefoot and has calluses, blood blistering, and ulceration
diabetic ulcer

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